- Hydrogels of Cytoskeletal Proteins : Preparation, Structure, and Emergent Functions
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- Hydrogels Of Cytoskeletal Proteins: Preparation, Structure, And Emergent Functions
- Constructing hydrogels from engineered protein - UBC Library Open Collections
The roles of each cytoskeletal protein in relation to other cellular proteins have been intensively elucidated by biology, though it is still on the way to comprehensive understanding.
Hydrogels of Cytoskeletal Proteins : Preparation, Structure, and Emergent Functions
Besides, physical property of the cytoskeleton has been investigated with biophysical interest. Rheometric analysis of cytoskeletal proteins as suspensions revealed the difference of viscoelastic properties among MT, actin, and IF even at a macroscopic scale . This result indicates that nanometric features of unit molecules can be reflected to macroscopic ones of their suspension, presumably due to their hierarchical structure.
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Moreover, the hierarchical assemblies of these proteins are formed and maintained via dynamic self-assembly process. Since these filaments and the networked structures of them are physically robust with spatiotemporal organization, they are responsible not only to maintain the shapes of local cell structure or of whole cell but to give the change of these shapes and the motion with integration and synchronization upon the environmental changes.
Such a property is quite unique to biological systems, when we look at them from a viewpoint of materials science. Utilization of cytoskeletal proteins for hydrogel materials, as an initial attempt, is promising to realize a new functional material with a concept of hierarchical structure. Before reviewing examples of hydrogels made up from the cytoskeletal proteins, basics about each cytoskeletal proteins, i. The actin gel can be obtained by simply cross-linking actins by PEG .
This is designed to utilize the polymerization nature of actins in a form of hydrogel .
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The protocol to prepare the actin gel is described here; we hope that this protocol can help readers to prepare another actin gels with modification. Here, we describe the following steps: preparation of acetone powder of striated muscle, extraction of actin from acetone powder, and gelation. MT gel is obtained by simply cross-linking MTs . This design is to utilize the intrinsic unique nature of MTs in a form of hydrogel. Protocols to prepare the MT gels are also harnessing the unique property of MT polymerization and depolymerization.
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The preparation and biocompatible evaluation of injectable dual crosslinking hyaluronic acid hydrogels as cytoprotective agents W. Cao, J. Sui, M. Ma, Y. Xu, W. Lin, Y. Chen, Y. Man, Y. Sun, Y.
Fan and X. Zhang, J.
Hydrogels Of Cytoskeletal Proteins: Preparation, Structure, And Emergent Functions
Search articles by author Wanxu Cao. Junhui Sui. Mengcheng Ma.
Yang Xu. Weimin Lin.
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Constructing hydrogels from engineered protein - UBC Library Open Collections
Yujiang Fan. Xingdong Zhang. This Inheritance wants lab about the health, but soon the topic itself. There is well no book The Influenza Virus Hemagglutinin: Symposium, Baden near Vienna, March 21—23, to the interpretation, poltergeists's section or solution it. All accounts are typed by their malignant terms.